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CCU Think Tank 2008
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CCU Think Tank 2008 Audio
Faculty Panel Discussion
Track 1
Reliability of K-ras mutation assessment
Track 2
Evaluation of K-ras mutation status in clinical practice
Track 3
Case discussion: A 64-year-old man with K-ras mutant, metastatic colon cancer previously treated with FOLFOX and FOLFIRI/bevacizumab
Track 4
Treatment options for patients with progressive, K-ras mutant colon cancer resistant to standard therapies
Track 5
Best supportive care versus EGFR inhibitors for patients with K-ras mutant colon cancer who have exhausted evidence-based treatment options
Track 6
CALGB-C80405: A Phase III randomized study of front-line cetuximab and/or bevacizumab in combination with FOLFOX or FOLFIRI
Track 7
Correlation between the IgE antibody and anaphylactic reactions to cetuximab
Track 8
Molecular predictors of response to systemic therapy
Track 9
Development of a multigene assay to assess risk of recurrence in colorectal cancer
Track 10
Role and clinical implications of K-ras mutation in tumorigenesis
Track 11
First BEAT: An international first-line bevacizumab expanded access trial in advanced colorectal cancer
Track 12
Cardiovascular considerations for patients treated with bevacizumab
Track 13
Hypertension as a predictor of response to bevacizumab
Track 14
Case discussion: A 50-year-old woman reluctant to stop therapy after receiving three years of treatment with chemotherapy/bevacizumab for metastatic rectal cancer
Track 15
Impact of continuing bevacizumab beyond disease progression
Track 16
Potential risks of long-term bevacizumab
Track 17
Continuous active therapy versus treatment holidays for patients with advanced disease
Track 18
Prognostic implications of calcified metastases
Track 19
Rationale for and clinical investigations of continuing bevacizumab beyond disease progression
Track 20
Inhibition of VEGF receptors in patients with disease progression on bevacizumab
Track 21
Research value and limitations of registry trials
Track 22
Phase II randomized trial of FOLFOX/cediranib versus FOLFOX/bevacizumab in previously treated metastatic colorectal cancer
Track 23
Challenges in the development of biologic agents
Track 24
Antitumor activity of tyrosine kinase inhibitors and potential long-term risks
Track 25
Mechanisms of action of bevacizumab
Track 26
Case discussion: A 38-year-old man with a tumor response to FOLFOX/bevacizumab for colon cancer metastases in the liver
Track 27
Pre- and/or postoperative adjuvant therapy for patients with resectable hepatic metastases
Track 28
Neoadjuvant therapy with chemotherapy and biologics in patients with hepatic metastases
Track 29
Hepatic toxicity secondary to chemotherapy
Track 30
Clinical use of preoperative chemotherapy for patients with resectable liver metastases
Track 31
Conversion of unresectable hepatic metastases to resectable disease with systemic therapy
Track 32
Postoperative treatment decision-making based on response to neoadjuvant therapy
Track 33
CAIRO2: A Phase III study of capecitabine/oxaliplatin/bevacizumab with or without cetuximab in advanced colorectal cancer
Track 34
PACCE: Irinotecan/bevacizumab with or without panitumumab as first-line treatment for metastatic colorectal cancer
Track 35
Potential implications of clinical trial results with combination anti-EGFR/anti-VEGF therapy in metastatic colorectal cancer
Track 36
NSABP-C-08 safety data: A Phase III study of adjuvant FOLFOX6 with or without bevacizumab in the treatment of Stage II/III colon cancer
Track 37
Case discussion: A 43-year-old man presenting with Stage II colon cancer and microcytic anemia
Track 38
Genotyping patients with a strong family history of colorectal cancer
Track 39
Development of a quantitative RT-PCR assay of 757 genes to predict risk of recurrence
Track 40
Prognostic versus predictive value of multigene assays
Track 41
Microsatellite instability predicts benefit from adjuvant irinotecan
Track 42
Case discussion: A 45-year-old woman presenting with lactic acidosis secondary to metastatic
colon cancer
Track 43
Maintenance therapy versus treatment holidays for patients with aggressively symptomatic colon cancer
Track 44
Rationale for examining the genomics of the outliers in clinical research
Track 45
Clinical implications of the OPTIMOX trial data for the use of treatment holidays
Track 46
Capecitabine and radiation therapy as neoadjuvant treatment of rectal cancer
Track 47
Postoperative treatment for patients with a complete response to neoadjuvant therapy
Track 48
Potential to exclude radiation therapy for patients with rectal cancer responding to systemic therapy
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