|  
               
              Home: 
              Web Guide 1: Select Publications 
              
              Select Publications 
            Araki Y et al. Dihydropyrimidine dehydrogenase activity and 
              thymidylate synthase level are associated with response to 5-fluorouracil 
              in human colorectal cancer. Kurume Med J 2001;48:93-8. Abstract 
             
              Bajetta E et al. Activity and safety of 
              capecitabine and irinotecan (CPT-11) in association as first line 
              chemotherapy in advanced colorectal cancer (ACRC). Eur J Cancer 
              2001;37(Suppl 6):293. Abstract 
             Becouarn Y et al. Randomized multicenter phase II study comparing 
              a combination of fluorouracil and folinic acid and alternating irinotecan 
              and oxaliplatin with oxaliplatin and irinotecan in fluorouracil-pretreated 
              metastatic colorectal cancer patients. J Clin Oncol 2001;19:4195-201. 
              Abstract 
             Falcone A et al. Sequence effect of irinotecan and fluorouracil 
              treatment on pharmacokinetics and toxicity in chemotherapy-naive 
              metastatic colorectal cancer patients. J Clin Oncol 2001;19:3456-62. 
              Abstract 
             Hoff PM et al. Comparison of oral capecitabine versus intravenous 
              fluorouracil plus leucovorin as first-line treatment in 605 patients 
              with metastatic colorectal cancer: Results of a randomized phase 
              III study. J Clin Oncol 2001;19:2282-92. Abstract 
             Kerr DJ et al. CPT-11 in combination with capecitabine as first 
              line chemotherapy for metastatic colorectal cancer (MCRC): Preliminary 
              results of a phase I/II study. Eur J Cancer 2001;37(Suppl 6):296. 
              Abstract 
             Saltz LB et al. Irinotecan plus fluorouracil and leucovorin 
              for metastatic colorectal cancer. Irinotecan Study Group. N 
              Engl J Med 2000;343:905-14. Abstract 
             
            Scheithauer W et al. Randomized multicenter phase II trial of 
              oxaliplatin plus irinotecan versus raltitrexed as first-line treatment 
              in advanced colorectal cancer. J Clin Oncol 2002;20:165-72. 
              Abstract 
             Schleucher N et al. Extended phase 
              I study of capecitabine and weekly irinotecan as first-line chemotherapy 
              in metastatic colorectal cancer. Eur J Cancer 2001;37(Suppl 
              6):290. Abstract 
             Twelves C et al. Capecitabine in combination 
              with oxaliplatin as first line therapy for patients (pts) with advanced 
              or metastatic colorectal cancer (ACRC): Preliminary results of an 
              international multicenter phase II study. Eur J Cancer 2001;37(Suppl 
              6):272. Abstract 
             Van Cutsem E et al. Oral capecitabine compared with intravenous 
              fluorouracil plus leucovorin in patients with metastatic colorectal 
              cancer: Results of a large phase III study. J Clin Oncol 2001;19:4097-106. 
              Abstract 
             Zeuli M et al. Oxaliplatin and capecitabine 
              in advanced colorectal cancer: A pilot study. Eur J Cancer 2001;37(Suppl 
              6):309. Abstract 
             
            
               
                |  
                   Pharmaceutical agents discussed in this program 
                  
                     
                      | capecitabine  | 
                      Xeloda® | 
                       Roche Laboratories, Inc. | 
                     
                     
                      | leucovorin  | 
                      Wellcovorin®  | 
                      GlaxoSmithKline | 
                     
                     
                      | irinotecan (CPT-11)  | 
                      Camptosar®  | 
                      Pharmacia Corporation | 
                     
                     
                      | oxaliplatin  | 
                      Eloxatin®  | 
                      Sanofi-Synthelabo, Inc | 
                     
                   
                 | 
               
             
               
             |